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Spleen Tyrosine Kinase Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia

The survival and proliferation of CLL cells depends on microenvironmental contacts in lymphoid organs. CD38 is a cell surface receptor that plays an important role in survival and proliferation signaling in CLL. In this study we demonstrate SYK's direct involvement in the CD38 signaling pathway...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Benkisser-Petersen, Marco, Buchner, Maike, Dörffel, Arlette, Dühren-von-Minden, Marcus, Claus, Rainer, Kläsener, Kathrin, Leberecht, Kerstin, Burger, Meike, Dierks, Christine, Jumaa, Hassan, Malavasi, Fabio, Reth, Michael, Veelken, Hendrik, Duyster, Justus, Zirlik, Katja
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201248/
https://ncbi.nlm.nih.gov/pubmed/28036404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169159
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