Exploiting native forces to capture chromosome conformation in mammalian cell nuclei

Mammalian interphase chromosomes fold into a multitude of loops to fit the confines of cell nuclei, and looping is tightly linked to regulated function. Chromosome conformation capture (3C) technology has significantly advanced our understanding of this structure‐to‐function relationship. However, a...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Brant, Lilija, Georgomanolis, Theodore, Nikolic, Milos, Brackley, Chris A, Kolovos, Petros, van Ijcken, Wilfred, Grosveld, Frank G, Marenduzzo, Davide, Papantonis, Argyris
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199122/
https://ncbi.nlm.nih.gov/pubmed/27940490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167311
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