Exploiting native forces to capture chromosome conformation in mammalian cell nuclei

Mammalian interphase chromosomes fold into a multitude of loops to fit the confines of cell nuclei, and looping is tightly linked to regulated function. Chromosome conformation capture (3C) technology has significantly advanced our understanding of this structure‐to‐function relationship. However, a...

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Detaylı Bibliyografya
Yayımlandı:Mol Syst Biol
Asıl Yazarlar: Brant, Lilija, Georgomanolis, Theodore, Nikolic, Milos, Brackley, Chris A, Kolovos, Petros, van Ijcken, Wilfred, Grosveld, Frank G, Marenduzzo, Davide, Papantonis, Argyris
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199122/
https://ncbi.nlm.nih.gov/pubmed/27940490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167311
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