Exploiting native forces to capture chromosome conformation in mammalian cell nuclei

Mammalian interphase chromosomes fold into a multitude of loops to fit the confines of cell nuclei, and looping is tightly linked to regulated function. Chromosome conformation capture (3C) technology has significantly advanced our understanding of this structure‐to‐function relationship. However, a...

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Bibliografische gegevens
Gepubliceerd in:Mol Syst Biol
Hoofdauteurs: Brant, Lilija, Georgomanolis, Theodore, Nikolic, Milos, Brackley, Chris A, Kolovos, Petros, van Ijcken, Wilfred, Grosveld, Frank G, Marenduzzo, Davide, Papantonis, Argyris
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199122/
https://ncbi.nlm.nih.gov/pubmed/27940490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167311
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