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Enhancers and silencers: an integrated and simple model for their function

Regulatory DNA elements such as enhancers, silencers and insulators are embedded in metazoan genomes, and they control gene expression during development. Although they fulfil different roles, they share specific properties. Herein we discuss some examples and a parsimonious model for their function...

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Detalhes bibliográficos
Main Authors: Kolovos, Petros, Knoch, Tobias A, Grosveld, Frank G, Cook, Peter R, Papantonis, Argyris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281776/
https://ncbi.nlm.nih.gov/pubmed/22230046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-5-1
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