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Enhancers and silencers: an integrated and simple model for their function

Regulatory DNA elements such as enhancers, silencers and insulators are embedded in metazoan genomes, and they control gene expression during development. Although they fulfil different roles, they share specific properties. Herein we discuss some examples and a parsimonious model for their function...

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Autori principali: Kolovos, Petros, Knoch, Tobias A, Grosveld, Frank G, Cook, Peter R, Papantonis, Argyris
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281776/
https://ncbi.nlm.nih.gov/pubmed/22230046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-5-1
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