TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning

BACKGROUND: The rearrangement of nucleosomes along the DNA fiber profoundly affects gene expression, but little is known about how signalling reshapes the chromatin landscape, in three-dimensional space and over time, to allow establishment of new transcriptional programs. RESULTS: Using micrococcal...

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Bibliografiska uppgifter
I publikationen:Genome Biol
Huvudupphovsmän: Diermeier, Sarah, Kolovos, Petros, Heizinger, Leonhard, Schwartz, Uwe, Georgomanolis, Theodore, Zirkel, Anne, Wedemann, Gero, Grosveld, Frank, Knoch, Tobias A, Merkl, Rainer, Cook, Peter R, Längst, Gernot, Papantonis, Argyris
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2014
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268828/
https://ncbi.nlm.nih.gov/pubmed/25608606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0536-6
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