Binding of nuclear factor κB to noncanonical consensus sites reveals its multimodal role during the early inflammatory response

Mammalian cells have developed intricate mechanisms to interpret, integrate, and respond to extracellular stimuli. For example, tumor necrosis factor (TNF) rapidly activates proinflammatory genes, but our understanding of how this occurs against the ongoing transcriptional program of the cell is far...

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Dades bibliogràfiques
Publicat a:Genome Res
Autors principals: Kolovos, Petros, Georgomanolis, Theodore, Koeferle, Anna, Larkin, Joshua D., Brant, Lilija, Nikolicć, Miloš, Gusmao, Eduardo G., Zirkel, Anne, Knoch, Tobias A., van Ijcken, Wilfred F., Cook, Peter R., Costa, Ivan G., Grosveld, Frank G., Papantonis, Argyris
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088591/
https://ncbi.nlm.nih.gov/pubmed/27633323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.210005.116
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