Radiogenomics to characterize regional genetic heterogeneity in glioblastoma

BACKGROUND: Glioblastoma (GBM) exhibits profound intratumoral genetic heterogeneity. Each tumor comprises multiple genetically distinct clonal populations with different therapeutic sensitivities. This has implications for targeted therapy and genetically informed paradigms. Contrast-enhanced (CE)-M...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Hu, Leland S., Ning, Shuluo, Eschbacher, Jennifer M., Baxter, Leslie C., Gaw, Nathan, Ranjbar, Sara, Plasencia, Jonathan, Dueck, Amylou C., Peng, Sen, Smith, Kris A., Nakaji, Peter, Karis, John P., Quarles, C. Chad, Wu, Teresa, Loftus, Joseph C., Jenkins, Robert B., Sicotte, Hugues, Kollmeyer, Thomas M., O'Neill, Brian P., Elmquist, William, Hoxworth, Joseph M., Frakes, David, Sarkaria, Jann, Swanson, Kristin R., Tran, Nhan L., Li, Jing, Mitchell, J. Ross
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193022/
https://ncbi.nlm.nih.gov/pubmed/27502248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now135
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