Multi-Parametric MRI and Texture Analysis to Visualize Spatial Histologic Heterogeneity and Tumor Extent in Glioblastoma

BACKGROUND: Genetic profiling represents the future of neuro-oncology but suffers from inadequate biopsies in heterogeneous tumors like Glioblastoma (GBM). Contrast-enhanced MRI (CE-MRI) targets enhancing core (ENH) but yields adequate tumor in only ~60% of cases. Further, CE-MRI poorly localizes in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hu, Leland S., Ning, Shuluo, Eschbacher, Jennifer M., Gaw, Nathan, Dueck, Amylou C., Smith, Kris A., Nakaji, Peter, Plasencia, Jonathan, Ranjbar, Sara, Price, Stephen J., Tran, Nhan, Loftus, Joseph, Jenkins, Robert, O’Neill, Brian P., Elmquist, William, Baxter, Leslie C., Gao, Fei, Frakes, David, Karis, John P., Zwart, Christine, Swanson, Kristin R., Sarkaria, Jann, Wu, Teresa, Mitchell, J. Ross, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658019/
https://ncbi.nlm.nih.gov/pubmed/26599106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141506
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