Radiogenomics to characterize regional genetic heterogeneity in glioblastoma

BACKGROUND: Glioblastoma (GBM) exhibits profound intratumoral genetic heterogeneity. Each tumor comprises multiple genetically distinct clonal populations with different therapeutic sensitivities. This has implications for targeted therapy and genetically informed paradigms. Contrast-enhanced (CE)-M...

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發表在:Neuro Oncol
Main Authors: Hu, Leland S., Ning, Shuluo, Eschbacher, Jennifer M., Baxter, Leslie C., Gaw, Nathan, Ranjbar, Sara, Plasencia, Jonathan, Dueck, Amylou C., Peng, Sen, Smith, Kris A., Nakaji, Peter, Karis, John P., Quarles, C. Chad, Wu, Teresa, Loftus, Joseph C., Jenkins, Robert B., Sicotte, Hugues, Kollmeyer, Thomas M., O'Neill, Brian P., Elmquist, William, Hoxworth, Joseph M., Frakes, David, Sarkaria, Jann, Swanson, Kristin R., Tran, Nhan L., Li, Jing, Mitchell, J. Ross
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
主題:
Basic and Translational Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193022/
https://ncbi.nlm.nih.gov/pubmed/27502248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now135
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