Radiogenomics to characterize regional genetic heterogeneity in glioblastoma

BACKGROUND: Glioblastoma (GBM) exhibits profound intratumoral genetic heterogeneity. Each tumor comprises multiple genetically distinct clonal populations with different therapeutic sensitivities. This has implications for targeted therapy and genetically informed paradigms. Contrast-enhanced (CE)-M...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hu, Leland S., Ning, Shuluo, Eschbacher, Jennifer M., Baxter, Leslie C., Gaw, Nathan, Ranjbar, Sara, Plasencia, Jonathan, Dueck, Amylou C., Peng, Sen, Smith, Kris A., Nakaji, Peter, Karis, John P., Quarles, C. Chad, Wu, Teresa, Loftus, Joseph C., Jenkins, Robert B., Sicotte, Hugues, Kollmeyer, Thomas M., O'Neill, Brian P., Elmquist, William, Hoxworth, Joseph M., Frakes, David, Sarkaria, Jann, Swanson, Kristin R., Tran, Nhan L., Li, Jing, Mitchell, J. Ross
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193022/
https://ncbi.nlm.nih.gov/pubmed/27502248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now135
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