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G-Quadruplex in the NRF2 mRNA 5′ Untranslated Region Regulates De Novo NRF2 Protein Translation under Oxidative Stress

Inhibition of protein synthesis serves as a general measure of cellular consequences of chemical stress. A few proteins are translated selectively and influence cell fate. How these proteins can bypass the general control of translation remains unknown. We found that low to mild doses of oxidants in...

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Pubblicato in:Mol Cell Biol
Autori principali: Lee, Sang C., Zhang, Jack, Strom, Josh, Yang, Danzhou, Dinh, Thai Nho, Kappeler, Kyle, Chen, Qin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192087/
https://ncbi.nlm.nih.gov/pubmed/27736771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00122-16
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