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Myocardial ischemic reperfusion induces de novo Nrf2 protein translation

Nrf2 is a bZIP transcription factor regulating the expression of antioxidant and detoxification genes. We have found that Nrf2 knockout mice have an increased infarction size in response to regional ischemic reperfusion and have a reduced degree of cardiac protection by means of ischemic preconditio...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Xu, Beibei, Zhang, Jack, Strom, Joshua, Lee, Sang, Chen, Qin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968415/
https://ncbi.nlm.nih.gov/pubmed/24915518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.06.002
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