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G-Quadruplex in the NRF2 mRNA 5′ Untranslated Region Regulates De Novo NRF2 Protein Translation under Oxidative Stress

Inhibition of protein synthesis serves as a general measure of cellular consequences of chemical stress. A few proteins are translated selectively and influence cell fate. How these proteins can bypass the general control of translation remains unknown. We found that low to mild doses of oxidants in...

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Publicado en:Mol Cell Biol
Main Authors: Lee, Sang C., Zhang, Jack, Strom, Josh, Yang, Danzhou, Dinh, Thai Nho, Kappeler, Kyle, Chen, Qin M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192087/
https://ncbi.nlm.nih.gov/pubmed/27736771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00122-16
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