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G-Quadruplex in the NRF2 mRNA 5′ Untranslated Region Regulates De Novo NRF2 Protein Translation under Oxidative Stress

Inhibition of protein synthesis serves as a general measure of cellular consequences of chemical stress. A few proteins are translated selectively and influence cell fate. How these proteins can bypass the general control of translation remains unknown. We found that low to mild doses of oxidants in...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Lee, Sang C., Zhang, Jack, Strom, Josh, Yang, Danzhou, Dinh, Thai Nho, Kappeler, Kyle, Chen, Qin M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192087/
https://ncbi.nlm.nih.gov/pubmed/27736771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00122-16
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