La Autoantigen Mediates Oxidant Induced De Novo Nrf2 Protein Translation

Nrf2 gene encodes a transcription factor that regulates the expression of a cluster of antioxidant and detoxification genes. Recent works from our laboratory indicate that oxidative stress causes rapid de novo synthesis of Nrf2 protein. We have found that 5′ Untranslated Region (5′UTR) of Nrf2 allow...

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Bibliografiske detaljer
Main Authors: Zhang, Jack, Dinh, Thai Nho, Kappeler, Kyle, Tsaprailis, George, Chen, Qin M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433904/
https://ncbi.nlm.nih.gov/pubmed/22207702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.015032
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