Mitochondrial Stress Induced p53 Attenuates HIF-1α Activity by Physical Association and Enhanced Ubiquitination

Retrograde signaling is a mechanism by which mitochondrial dysfunction is communicated to the nucleus for inducing a metabolic shift essential for cell survival. Previously we showed that partial mtDNA depletion in different cell types induced mitochondrial retrograde signaling pathway (MtRS) involv...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Chowdhury, Anindya Roy, Long, Apple, Fuchs, Serge, Rustgi, Anil, Avadhani, Narayan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192009/
https://ncbi.nlm.nih.gov/pubmed/27345397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.211
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