Cigarette Smoke Toxins-Induced Mitochondrial Dysfunction and Pancreatitis Involves Aryl Hydrocarbon Receptor Mediated Cyp1 Gene Expression: Protective Effects of Resveratrol

We previously reported that mitochondrial CYP1 enzymes participate in the metabolism of polycyclic aromatic hydrocarbons and other carcinogens leading to mitochondrial dysfunction. In this study, using Cyp1b1(−)(/)(−), Cyp1a1/1a2(−)(/)(−), and Cyp1a1/1a2/1b1(−)(/)(−) mice, we observed that cigarette...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxicol Sci
Prif Awduron: Ghosh, Jyotirmoy, Chowdhury, Anindya Roy, Srinivasan, Satish, Chattopadhyay, Mrittika, Bose, Moumita, Bhattacharya, Sabyasachi, Raza, Haider, Fuchs, Serge Y, Rustgi, Anil K, Gonzalez, Frank J, Avadhani, Narayan G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
AHR-Mediated Effects of Cigarette Smoke
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260170/
https://ncbi.nlm.nih.gov/pubmed/30165701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy206
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