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Silencing of IkBβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo
A number of studies show that mitochondrial DNA (mtDNA) depletion and attendant activation of retrograde signaling induces tumor progression. We have reported previously that activation of a novel nuclear factor-Kappa B pathway is critical for the propagation of mitochondrial retrograde signaling, w...
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主要な著者: | , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Oxford University Press
2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514893/ https://ncbi.nlm.nih.gov/pubmed/22637744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs190 |
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