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Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration

Mechanisms of brain and retinal iron homeostasis have become subjects of increased interest after the discovery of elevated iron levels in brains of patients with Alzheimer's disease and retinas of patients with age-related macular degeneration. To determine whether the ferroxidase ceruloplasmi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hahn, Paul, Qian, Ying, Dentchev, Tzvete, Chen, Lin, Beard, John, Harris, Zena Leah, Dunaief, Joshua L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC518844/
https://ncbi.nlm.nih.gov/pubmed/15365174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405146101
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