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Ceruloplasmin/Hephaestin Knockout Mice Model Morphologic and Molecular Features of AMD
PURPOSE: Iron is an essential element in human metabolism but also is a potent generator of oxidative damage with levels that increase with age. Several studies suggest that iron accumulation may be a factor in age-related macular degeneration (AMD). In prior studies, both iron overload and features...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2569891/ https://ncbi.nlm.nih.gov/pubmed/18326691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1472 |
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