Heregulin ameliorates the dystrophic phenotype in mdx mice

Duchenne's muscular dystrophy (DMD) is a fatal neuromuscular disease caused by absence of dystrophin. Utrophin is a chromosome 6-encoded dystrophin-related protein (DRP), sharing functional motifs with dystrophin. Utrophin's ability to compensate for dystrophin during development and when...

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Autori principali: Krag, Thomas O. B., Bogdanovich, Sasha, Jensen, Claus J., Fischer, M. Dominik, Hansen-Schwartz, Jacob, Javazon, Elisabeth H., Flake, Alan W., Edvinsson, Lars, Khurana, Tejvir S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC518764/
https://ncbi.nlm.nih.gov/pubmed/15365169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405972101
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