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Rapamycin Ameliorates Dystrophic Phenotype in mdx Mouse Skeletal Muscle

Duchenne muscular dystrophy (DMD) is an X-linked, lethal, degenerative disease that results from mutations in the dystrophin gene, causing necrosis and inflammation in skeletal muscle tissue. Treatments that reduce muscle fiber destruction and immune cell infiltration can ameliorate DMD pathology. W...

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Detalhes bibliográficos
Main Authors: Eghtesad, Saman, Jhunjhunwala, Siddharth, Little, Steven R, Clemens, Paula R
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188871/
https://ncbi.nlm.nih.gov/pubmed/21607286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00256
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