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Rapamycin Ameliorates Dystrophic Phenotype in mdx Mouse Skeletal Muscle

Duchenne muscular dystrophy (DMD) is an X-linked, lethal, degenerative disease that results from mutations in the dystrophin gene, causing necrosis and inflammation in skeletal muscle tissue. Treatments that reduce muscle fiber destruction and immune cell infiltration can ameliorate DMD pathology. W...

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Bibliografiske detaljer
Main Authors: Eghtesad, Saman, Jhunjhunwala, Siddharth, Little, Steven R, Clemens, Paula R
Format: Artigo
Sprog:Inglês
Udgivet: ScholarOne 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188871/
https://ncbi.nlm.nih.gov/pubmed/21607286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00256
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