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Effect of rapamycin on immunity induced by vector-mediated dystrophin expression in mdx skeletal muscle
Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene. Therapeutic gene replacement of a dystrophin cDNA into dystrophic muscle can provide functional dystrophin protein to the tissue. However, vector-mediated gene transfer is limited by anti-vector and anti-transgene host...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347316/ https://ncbi.nlm.nih.gov/pubmed/22570764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00399 |
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