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Notch Activation Induces Endothelial Cell Cycle Arrest and Participates in Contact Inhibition: Role of p21(Cip1) Repression

Although previous studies demonstrate that appropriate Notch signaling is required during angiogenesis and in vascular homeostasis, the mechanisms by which Notch regulates vascular function remain to be elucidated. Here, we show that activation of the Notch pathway by the ligand Jagged1 reduces the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Noseda, Michela, Chang, Linda, McLean, Graeme, Grim, Jonathan E., Clurman, Bruce E., Smith, Laura L., Karsan, Aly
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC517869/
https://ncbi.nlm.nih.gov/pubmed/15456857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.8813-8822.2004
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