Notch Activation Induces Endothelial Cell Cycle Arrest and Participates in Contact Inhibition: Role of p21(Cip1) Repression

Although previous studies demonstrate that appropriate Notch signaling is required during angiogenesis and in vascular homeostasis, the mechanisms by which Notch regulates vascular function remain to be elucidated. Here, we show that activation of the Notch pathway by the ligand Jagged1 reduces the...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Noseda, Michela, Chang, Linda, McLean, Graeme, Grim, Jonathan E., Clurman, Bruce E., Smith, Laura L., Karsan, Aly
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2004
Konular:
Cell Growth and Development
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517869/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15456857/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.20.8813-8822.2004
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