BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53

The acquisition of drug resistance is a persistent clinical problem limiting the successful treatment of glioblastoma (GBM). However, the molecular mechanisms by which initially chemoresponsive tumors develop therapeutic resistance remain poorly understood. In this study, we report that BACH1, a hem...

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Foilsithe in:Sci Rep
Main Authors: Nie, Er, Jin, Xin, Wu, Weining, Yu, Tianfu, Zhou, Xu, Zhi, Tongle, Shi, Zhumei, Zhang, Junxia, Liu, Ning, You, Yongping
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175153/
https://ncbi.nlm.nih.gov/pubmed/28000777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39743
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