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BACH1 Promotes Temozolomide Resistance in Glioblastoma through Antagonizing the Function of p53

The acquisition of drug resistance is a persistent clinical problem limiting the successful treatment of glioblastoma (GBM). However, the molecular mechanisms by which initially chemoresponsive tumors develop therapeutic resistance remain poorly understood. In this study, we report that BACH1, a hem...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nie, Er, Jin, Xin, Wu, Weining, Yu, Tianfu, Zhou, Xu, Zhi, Tongle, Shi, Zhumei, Zhang, Junxia, Liu, Ning, You, Yongping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175153/
https://ncbi.nlm.nih.gov/pubmed/28000777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39743
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