EZH2 alteration driven by microRNA-524-5p and microRNA-324-5p promotes cell proliferation and temozolomide resistance in glioma

Recent data have been shown that EZH2 is a critical oncogene via the repression of tumor suppressor genes in human cancers. In our study, we performed a genome-wide miRNA screen with a bioinformatics analysis to identify EZH2 specific miRNAs. Of these miRNAs, miR-524-5p and miR-324-5p were decreased...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Zhi, Tongle, Yu, Tianfu, Pan, Minhong, Nie, Er, Wu, Weining, Wang, Xiefeng, Liu, Ning, You, Yongping, Wang, Yingyi, Zhang, Junxia
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707096/
https://ncbi.nlm.nih.gov/pubmed/29221202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21996
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