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Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy

Mitophagy is a fundamental process that determines mitochondrial quality and homeostasis. Several mitophagy receptors, including the newly identified FUNDC1, mediate selective removal of damaged or superfluous mitochondria through their specific interaction with LC3. However, the precise mechanism b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Kuang, Yao, Ma, Kaili, Zhou, Changqian, Ding, Pengfei, Zhu, Yushan, Chen, Quan, Xia, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173264/
https://ncbi.nlm.nih.gov/pubmed/27653272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238552
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