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Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy
Mitophagy is a fundamental process that determines mitochondrial quality and homeostasis. Several mitophagy receptors, including the newly identified FUNDC1, mediate selective removal of damaged or superfluous mitochondria through their specific interaction with LC3. However, the precise mechanism b...
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Veröffentlicht in: | Autophagy |
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Hauptverfasser: | , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Taylor & Francis
2016
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173264/ https://ncbi.nlm.nih.gov/pubmed/27653272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238552 |
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