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Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy

Mitophagy is a fundamental process that determines mitochondrial quality and homeostasis. Several mitophagy receptors, including the newly identified FUNDC1, mediate selective removal of damaged or superfluous mitochondria through their specific interaction with LC3. However, the precise mechanism b...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Kuang, Yao, Ma, Kaili, Zhou, Changqian, Ding, Pengfei, Zhu, Yushan, Chen, Quan, Xia, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173264/
https://ncbi.nlm.nih.gov/pubmed/27653272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238552
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