Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy

Mitophagy is a fundamental process that determines mitochondrial quality and homeostasis. Several mitophagy receptors, including the newly identified FUNDC1, mediate selective removal of damaged or superfluous mitochondria through their specific interaction with LC3. However, the precise mechanism b...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Autophagy
Main Authors: Kuang, Yao, Ma, Kaili, Zhou, Changqian, Ding, Pengfei, Zhu, Yushan, Chen, Quan, Xia, Bin
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Basic Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173264/
https://ncbi.nlm.nih.gov/pubmed/27653272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238552
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