Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy

Mitophagy is a fundamental process that determines mitochondrial quality and homeostasis. Several mitophagy receptors, including the newly identified FUNDC1, mediate selective removal of damaged or superfluous mitochondria through their specific interaction with LC3. However, the precise mechanism b...

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Bibliografische gegevens
Gepubliceerd in:Autophagy
Hoofdauteurs: Kuang, Yao, Ma, Kaili, Zhou, Changqian, Ding, Pengfei, Zhu, Yushan, Chen, Quan, Xia, Bin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2016
Onderwerpen:
Basic Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173264/
https://ncbi.nlm.nih.gov/pubmed/27653272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238552
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