Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy

Mitophagy is a fundamental process that determines mitochondrial quality and homeostasis. Several mitophagy receptors, including the newly identified FUNDC1, mediate selective removal of damaged or superfluous mitochondria through their specific interaction with LC3. However, the precise mechanism b...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Kuang, Yao, Ma, Kaili, Zhou, Changqian, Ding, Pengfei, Zhu, Yushan, Chen, Quan, Xia, Bin
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
Materias:
Basic Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173264/
https://ncbi.nlm.nih.gov/pubmed/27653272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1238552
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