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PCR mediated recombination impacts the analysis of hepatitis B Virus covalently closed circular DNA

BACKGROUND: The replication of HBV involves the production of covalently closed circular DNA (cccDNA) from the HBV genome through the repair of virion relaxed circular DNA (rcDNA) in the virion. As cccDNA is the transcription template for HBV genomes, it needs to be eliminated from hepatocytes if th...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Retrovirology
Asıl Yazarlar: Suspène, Rodolphe, Thiers, Valérie, Vartanian, Jean-Pierre, Wain-Hobson, Simon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5168874/
https://ncbi.nlm.nih.gov/pubmed/27998270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0318-1
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