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DNA recombination during PCR.

PCR co-amplification of two distinct HIV1 tat gene sequences lead to the formation of recombinant DNA molecules. The frequency of such recombinants, up to 5.4% of all amplified molecules, could be decreased 2.7 fold by a 6 fold increase in Taq DNA polymerase elongation time. Crossover sites mapped e...

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Sonraí Bibleagrafaíochta
Main Authors: Meyerhans, A, Vartanian, J P, Wain-Hobson, S
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1990
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC330584/
https://ncbi.nlm.nih.gov/pubmed/2186361
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