Llwytho...

Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo

Because the replication of hepatitis B virus (HBV) proceeds via an obligatory reverse transcription step in the viral capsid, cDNA is potentially vulnerable to editing by cytidine deaminases of the APOBEC3 family. To date only two edited HBV genomes, referred to as G → A hypermutants, have been desc...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Suspène, Rodolphe, Guétard, Denise, Henry, Michel, Sommer, Peter, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149401/
https://ncbi.nlm.nih.gov/pubmed/15919829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408223102
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