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APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase
In the absence of the viral vif gene, human immunodeficiency virus (HIV) may be restricted by the APOBEC3G gene on chromosome 22. The role of the HIV Vif protein is to exclude host cell APOBEC3G from the budding virion. As APOBEC3G shows sequence homology to cytidine deaminases, it is presumed that...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419444/ https://ncbi.nlm.nih.gov/pubmed/15121899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh554 |
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