APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase

In the absence of the viral vif gene, human immunodeficiency virus (HIV) may be restricted by the APOBEC3G gene on chromosome 22. The role of the HIV Vif protein is to exclude host cell APOBEC3G from the budding virion. As APOBEC3G shows sequence homology to cytidine deaminases, it is presumed that...

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Autori principali: Suspène, Rodolphe, Sommer, Peter, Henry, Michel, Ferris, Stéphane, Guétard, Denise, Pochet, Sylvie, Chester, Ann, Navaratnam, Naveenan, Wain-Hobson, Simon, Vartanian, Jean-Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC419444/
https://ncbi.nlm.nih.gov/pubmed/15121899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh554
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