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Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication
The human immunodeficiency virus (HIV) Vif protein blocks incorporation of two host cell cytidine deaminases, APOBEC3F and 3G, into the budding virion. Not surprisingly, on a vif background nascent minus strand DNA can be extensively edited leaving multiple uracil residues. Editing occurs preferenti...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635257/ https://ncbi.nlm.nih.gov/pubmed/16963778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl555 |
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