A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection

Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) was first identified in 2012, and it continues to threaten human health worldwide. No MERS vaccines are licensed for human use, reinforcing the urgency to develop safe and efficacious vaccines to prevent MERS. MERS-CoV spike protein form...

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Bibliographische Detailangaben
Veröffentlicht in:Virology
Hauptverfasser: Tai, Wanbo, Zhao, Guangyu, Sun, Shihun, Guo, Yan, Wang, Yufei, Tao, Xinrong, Tseng, Chien-Te K., Li, Fang, Jiang, Shibo, Du, Lanying, Zhou, Yusen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Inc. 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167628/
https://ncbi.nlm.nih.gov/pubmed/27750111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.10.005
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