Intranasally administered peptidic viral fusion inhibitor protected hDPP4 transgenic mice from MERS-CoV infection

BACKGROUND: Middle East respiratory syndrome coronavirus (MERS-CoV), a new coronavirus that emerged in 2012, causes severe and fatal acute respiratory illness in man. Its high mortality (roughly 38%) has raised public fear worldwide, calling for the development of effective and safe therapeutics to...

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發表在:Lancet
Main Authors: Jiang, Shibo, Tao, Xinrong, Xia, Shuai, Garron, Tania, Yu, Fei, Du, Lanying, Lu, Lu, Tseng, Chien-Te K
格式: Artigo
語言:Inglês
出版: Elsevier Ltd. 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159274/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(15)00625-X
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