A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection

Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) was first identified in 2012, and it continues to threaten human health worldwide. No MERS vaccines are licensed for human use, reinforcing the urgency to develop safe and efficacious vaccines to prevent MERS. MERS-CoV spike protein form...

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Publicado no:Virology
Main Authors: Tai, Wanbo, Zhao, Guangyu, Sun, Shihun, Guo, Yan, Wang, Yufei, Tao, Xinrong, Tseng, Chien-Te K., Li, Fang, Jiang, Shibo, Du, Lanying, Zhou, Yusen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167628/
https://ncbi.nlm.nih.gov/pubmed/27750111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.10.005
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