Preparation and physicochemical characterization of spray-dried and jet-milled microparticles containing bosentan hydrate for dry powder inhalation aerosols

The objectives of this study were to prepare bosentan hydrate (BST) microparticles as dry powder inhalations (DPIs) via spray drying and jet milling under various parameters, to comprehensively characterize the physicochemical properties of the BST hydrate microparticles, and to evaluate the aerosol...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Lee, Hyo-Jung, Kang, Ji-Hyun, Lee, Hong-Goo, Kim, Dong-Wook, Rhee, Yun-Seok, Kim, Ju-Young, Park, Eun-Seok, Park, Chun-Woong
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167478/
https://ncbi.nlm.nih.gov/pubmed/28008226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S120356
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