Preparation and physicochemical characterization of spray-dried and jet-milled microparticles containing bosentan hydrate for dry powder inhalation aerosols

The objectives of this study were to prepare bosentan hydrate (BST) microparticles as dry powder inhalations (DPIs) via spray drying and jet milling under various parameters, to comprehensively characterize the physicochemical properties of the BST hydrate microparticles, and to evaluate the aerosol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drug Des Devel Ther
Egile Nagusiak: Lee, Hyo-Jung, Kang, Ji-Hyun, Lee, Hong-Goo, Kim, Dong-Wook, Rhee, Yun-Seok, Kim, Ju-Young, Park, Eun-Seok, Park, Chun-Woong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2016
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167478/
https://ncbi.nlm.nih.gov/pubmed/28008226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S120356
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