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The Effect of Particle Size and Surface Roughness of Spray-Dried Bosentan Microparticles on Aerodynamic Performance for Dry Powder Inhalation

The purpose of this study was to prepare spray dried bosentan microparticles for dry powder inhaler and to characterize its physicochemical and aerodynamic properties. The microparticles were prepared from ethanol/water solutions containing bosentan using spray dryer. Three types of formulations (SD...

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Kwon, Yong-Bin, Kang, Ji-Hyun, Han, Chang-Soo, Kim, Dong-Wook, Park, Chun-Woong
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465523/
https://ncbi.nlm.nih.gov/pubmed/32823545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12080765
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