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The Effect of Particle Size and Surface Roughness of Spray-Dried Bosentan Microparticles on Aerodynamic Performance for Dry Powder Inhalation

The purpose of this study was to prepare spray dried bosentan microparticles for dry powder inhaler and to characterize its physicochemical and aerodynamic properties. The microparticles were prepared from ethanol/water solutions containing bosentan using spray dryer. Three types of formulations (SD...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Kwon, Yong-Bin, Kang, Ji-Hyun, Han, Chang-Soo, Kim, Dong-Wook, Park, Chun-Woong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465523/
https://ncbi.nlm.nih.gov/pubmed/32823545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12080765
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