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The Effect of Particle Size and Surface Roughness of Spray-Dried Bosentan Microparticles on Aerodynamic Performance for Dry Powder Inhalation

The purpose of this study was to prepare spray dried bosentan microparticles for dry powder inhaler and to characterize its physicochemical and aerodynamic properties. The microparticles were prepared from ethanol/water solutions containing bosentan using spray dryer. Three types of formulations (SD...

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Dettagli Bibliografici
Pubblicato in:Pharmaceutics
Autori principali: Kwon, Yong-Bin, Kang, Ji-Hyun, Han, Chang-Soo, Kim, Dong-Wook, Park, Chun-Woong
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465523/
https://ncbi.nlm.nih.gov/pubmed/32823545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12080765
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