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Theophylline Cocrystals Prepared by Spray Drying: Physicochemical Properties and Aerosolization Performance

The purpose of this work was to characterize theophylline (THF) cocrystals prepared by spray drying in terms of the physicochemical properties and inhalation performance when aerosolized from a dry powder inhaler. Cocrystals of theophylline with urea (THF-URE), saccharin (THF-SAC) and nicotinamide (...

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Detalhes bibliográficos
Main Authors: Alhalaweh, Amjad, Kaialy, Waseem, Buckton, Graham, Gill, Hardyal, Nokhodchi, Ali, Velaga, Sitaram P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581642/
https://ncbi.nlm.nih.gov/pubmed/23297166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9883-3
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