Theophylline Cocrystals Prepared by Spray Drying: Physicochemical Properties and Aerosolization Performance

The purpose of this work was to characterize theophylline (THF) cocrystals prepared by spray drying in terms of the physicochemical properties and inhalation performance when aerosolized from a dry powder inhaler. Cocrystals of theophylline with urea (THF-URE), saccharin (THF-SAC) and nicotinamide (...

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Main Authors: Alhalaweh, Amjad, Kaialy, Waseem, Buckton, Graham, Gill, Hardyal, Nokhodchi, Ali, Velaga, Sitaram P.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581642/
https://ncbi.nlm.nih.gov/pubmed/23297166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9883-3
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