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The function of orthologues of the human Parkinson’s disease gene LRRK2 across species: implications for disease modeling in preclinical research
In the period since LRRK2 (Leucine-Rich Repeat Kinase 2) was identified as a causal gene for late-onset autosomal-dominant parkinsonism, a great deal of work has been aimed at understanding whether the LRRK2 protein might be a druggable target for Parkinson’s disease (PD). As part of this effort, an...
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| Vydáno v: | Biochem J |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5165698/ https://ncbi.nlm.nih.gov/pubmed/26811536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150985 |
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