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LRRK2 links genetic and sporadic Parkinson’s disease

The past two decades in research has revealed the importance of leucine-rich repeat kinase 2 (LRRK2) in both monogenic and sporadic forms of Parkinson’s disease (PD). In families, mutations in LRRK2 can cause PD with age-dependent but variable penetrance and genome-wide association studies have foun...

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Bibliographic Details
Published in:Biochem Soc Trans
Main Authors: Kluss, Jillian H., Mamais, Adamantios, Cookson, Mark R.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563926/
https://ncbi.nlm.nih.gov/pubmed/30837320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20180462
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