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The role of LRRK2 dysfunction in Parkinson’s disease

Parkinson’s disease is a common and usually sporadic neurodegenerative disorder. However, a subset of cases are inherited and, of these, mutations in the gene encoding Leucine-rich repeat kinase 2 (LRRK2) are the most frequent known genetic cause of disease. Here, we will discuss recent progress in...

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Detalhes bibliográficos
Publicado no:Expert Rev Mol Med
Main Authors: Kumar, Azad, Cookson, Mark R
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672634/
https://ncbi.nlm.nih.gov/pubmed/21676337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S146239941100192X
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