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Anticorrelated motions as a driving force in enzyme catalysis: The dehydrogenase reaction

Molecular dynamics and cross-correlation analysis of the horse liver alcohol dehydrogenase HLADH·NAD(+)·PhCH(2)O(–) complex has established anticorrelated motions between the NAD(+)-binding domain and other portions of the enzyme. Four pairs of anticorrelated interactions are (i and ii) cofactor-bin...

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Hlavní autoři: Luo, Jia, Bruice, Thomas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC516540/
https://ncbi.nlm.nih.gov/pubmed/15331786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405502101
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