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The mechanism of catalysis of the chorismate to prephenate reaction by the Escherichia coli mutase enzyme

Molecular dynamics studies of the Escherichia coli chorismate mutase (EcCM), containing at the active site chorismate and in turn the transition state (TS), have been performed. The simulations show that TS is not bound any tighter than chorismate. Comparison of average polar interactions show they...

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Bibliografski detalji
Glavni autori: Hur, Sun, Bruice, Thomas C.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC122163/
https://ncbi.nlm.nih.gov/pubmed/11818529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022628599
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