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The proficiency of a thermophilic chorismate mutase enzyme is solely through an entropic advantage in the enzyme reaction
A study of the Thermus thermophilus chorismate mutase (TtCM) is described by using quantum mechanics (self-consistent-charge density-functional tight binding)/molecular mechanics, umbrella sampling, and the weighted histogram analysis method. The computed free energies of activation for the reaction...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2005
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1317962/ https://ncbi.nlm.nih.gov/pubmed/16344484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509234102 |
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